By C. H. A. Meyer, A. Detta, C. Kudoh (auth.), Assoc. Professor Dr. Björn A. Meyerson, Professor Dr. Christoph Ostertag (eds.)

This quantity includes chosen contributions from the XIth assembly of the eu Society for Stereotactic and useful Neurosurgery held in September 1994 in Antalyaffurkey. many of the papers care for the numerous healing and technical developments made during this box of neurosurgery. The emergence of latest stereotactic methodologies akin to frameless stereotaxy and other kinds of neuronavigation became an critical device for every type of neurosurgical operations. more and more younger neurosurgeons takes an curiosity within the neurosurgical ways to the therapy of circulate issues, persistent discomfort and epilepsy. it is a transparent signal ofthe transforming into know-how of the lengthy overlooked indisputable fact that those neurosurgical remedies may be provided to giant sufferer populations. Neurotransplantation as a unique remedy of Parkinson's ailment has lead the way for the applying of this expertise for different symptoms. The pioneering paintings played via the overdue Edward Hitchcock is reviewed the following. there's a renewed curiosity in pallidotomy for facing definite kinds of Parkinson's disorder and sure facets of this operation are mentioned in one other paper. growth within the neurosurgical therapy of soreness is handled by way of contributions on sophisticated strategies of percutaneous cordotomy, DREZ operations and demanding reviews of spinal wire stimulation. a singular strategy is a file at the reviews of treating melanoma ache by means of intraspinal implantation of chromaffin cells. a number of contributions disguise the $64000 problems with novel strategies for the examine of neural disorder, peroperative tracking with puppy, microrecording, magneto-encephalography and different techniques.

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Additional info for Advances in Stereotactic and Functional Neurosurgery 11: Proceedings of the 11th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Antalya 1994

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One paraplegic patient died of pulmonary embolism, in this case the spasms scores was reduced of 3 to 1. It must be questioned for paraplegic patients, that the spasms might not be totally suppressed, to avoid venous stasis and for keeping muscular trophicity in the legs [15,18]. e. e. spontaneous or induced). In P. Mertens et al. e. the minimal stimulus intensity required to elicit a spasm) and their intensity, as measured by the amplitude and duration of the EMG response in flexor muscles. Both parameters proved to be very significantly influenced by chronic baclofen infusion, which abolished or strongly attenuated flexion responses in all our patients (Fig.

In the patients with hyperactive bladder (9 patients), inconstant results was observed. The uninhibited contractions were reduced or suppressed in 50% of cases, even if a optimal control of hypertonia and spasms oflower limbs was present in all patients during urodynamic study. We can suppose that the "effective dose" able to suppress the lower limb spasticity is, in some cases, not enough to achieve an optimal effect on the hyperactive bladder. In experimental studies, the depression of micturition reflex was obtained only with very high doses, probably caused by depression of supraspinal centers (ponto-mesencephalic micturation center) [9,14].

Baclofen Effects on Lower Urinary Tract Function After baclofen infusion, no change was reported by patients with normal miction. In the patients with hyperactive bladder (9 patients), inconstant results was observed. The uninhibited contractions were reduced or suppressed in 50% of cases, even if a optimal control of hypertonia and spasms oflower limbs was present in all patients during urodynamic study. We can suppose that the "effective dose" able to suppress the lower limb spasticity is, in some cases, not enough to achieve an optimal effect on the hyperactive bladder.

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